Listar por autor "Esteva, Isabel"
Mostrando ítems 1-4 de 4
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Analysis of Four Polymorphisms Located at the Promoter of the Estrogen Receptor Alpha ESR1 Gene in a Population With Gender Incongruence
Fernández, Rosa; Delgado-Zayas, Enrique; Ramírez, Karla; Cortés-Cortés, Joselyn; Gómez-Gil, Esther; Esteva, Isabel; Almaraz, Mari Cruz; Guillamón, Antonio; Pásaro, Eduardo (2020)[Abstract] Introduction: Gender incongruence defines a state in which individuals feel discrepancy between the sex assigned at birth and their gender. Some of these people make a social transition from male to female ... -
Gender-Affirming Hormone Therapy Modifies the CpG Methylation Pattern of the ESR1 Gene Promoter After Six Months of Treatment in Transmen
Fernández, Rosa; Ramírez, Karla; Gómez-Gil, Esther; Cortés-Cortés, Joselyn; Mora, Mireia; Aranda, Gloria; Delgado Zayas, Enrique; Esteva, Isabel; Almaraz, Mari Cruz; Guillamón, Antonio; Pásaro, Eduardo (2020)[Abstract] Background Brain sexual differentiation is a process that results from the effects of sex steroids on the developing brain. Evidence shows that epigenetics plays a main role in the formation of enduring brain ... -
Implications of the Estrogen Receptor Coactivators SRC1 and SRC2 in the Biological Basis of Gender Incongruence
Del Valle Ramírez, Karla; Fernández, Rosa; Delgado-Zayas, Enrique; Gómez-Gil, Esther; Esteva, Isabel; Guillamon, Antonio; Pásaro, Eduardo (2021)[Abstract] Introduction Brain sexual differentiation results from the effects of sex steroids on the developing brain. The presumptive route for brain masculinization is the direct induction of gene expression via activation ... -
Molecular basis of Gender Dysphoria: androgen and estrogen receptor interaction
Fernández, Rosa; Guillamón, Antonio; Cortés-Cortés, Joselyn; Gómez-Gil, Esther; Jácome, M. A.; Esteva, Isabel; Almaraz, Mari Cruz; Mora, Mireia; Aranda, Gloria; Pásaro, Eduardo (Elsevier, 2018-08-27)[Abstract] Background: Polymorphisms in sex steroid receptors have been associated with transsexualism. However, published replication studies have yielded inconsistent findings, possibly because of a limited sample size ...